Detection and Identification of Designer Drugs, a title in the Emerging Issues in Analytical Chemistry series, presents both an overview and a guide to techniques for anyone studying or engaging in designer drug analysis. Proliferation of the synthesis and use of designer drugs is a serious public health problem with social, economic and legal implications. Whether abuse is studied at the population level or the individual level, researchers need both background and highly detailed technical information on specific drugs and drug classes in order to combat the proliferation and highly damaging consequences of these substances. Author Brian F. Thomas provides a comprehensive discussion that emphasizes the potential threat to society, presents the ongoing challenges confronting the various laboratory approaches to detection and identification of new chemical entities and informs the development of improved analytical solutions for use in legislation, law enforcement and treatment.
1. Introduction 2. Chemical classes of commonly encountered abused substances Opioids Cannabinoids Dissociative anesthetics Stimulants and entactogens Benzodiazepines Steroids 3. Analytical methods for detection and identification Analysis of bulk chemical substances: Stability assessment Analysis of dosage formulations: Exposure assessment Forensic analysis in biological fluids: Biomarkers of exposure Wastewater analysis: Estimation of prevalence and type Home and workplace drug testing: National laboratory certification program 4. Informatics and monitoring Chemoinformatics National forensic laboratory information system EMCDDA Websites and forums 5. Best practices and new approaches