Main description:

This new volume documents the transition from the development of electrochemical monitoring of brain function, now more than 40 years old, to fundamental neuroscience. This includes the links of molecular neuroscience to biobehavior, to a molecular understanding of neurologically-linked diseases and to the investigation of neuroactive molecules made possible by new detection methodology. This work should be of interest to a broad audience, especially those who are engaged in neuroscience research, for example in drug discovery, but are not familiar with electrochemical methodology.

Contents:

Using Biosensors to Probe Fundamental Questions of Sleep; Cortical Colinergic Transients for Cue Detection and Attentional Mode Shifts; Real-Time Measurement of ATP and Adenosine in the Nervous System; Electrochemical Detection of Adenosine In Vivo; Real time In Vivo Neurotransmitter Measurements using Enzyme-Based Ceramic Microelectrode Arrays: What We Have Learned About Glutamate Signaling; Enzyme-Based Microbiosensors for Selective Quantification of Rapid Molecular Fluctuations in Brain Tissue; Monitoring and Modulating Dopamine Release and Unit Activity in Real-Time; Quantitative Chemical Measurements of Vesicular Transmitters with Single Cell Amperometry and Electrochemical Cytometry; Coupling Voltammetry with Optogenetics to Reveal Axonal Control of Dopamine Transmission by Striatal Acetylcholine; Electrochemical Recordings During Deep Brain Stimulation in Animals and Humans: WINCS, MINCS, and Closed Loops DBS; Sweet Leaf: Neurochemical Advances Reveal How Cannabinoids Affect Brain Dopamine Concentrations; Probing Serotonin Neurotransmission: Implications for Neuropsychiatric Disorders; Voltammetric Analysis of Loss and Gain of Dopamine Function; Measurements of Dopamine Release and Uptake in Huntington's Disease Model Rodents; Characterizing Neuropeptide Release: From Isolated Cells to Intact Animals; Advancing Chronic Intracortical Electrode Recording Function; Measurement of Cytokines in the Brain;