Main description:

This new edition provides clinicians and trainees with guidance on the latest clinical research techniques and publishing in medical literature.

Divided into six sections, the book begins with an overview of research and evidence-based medicine, then discusses the strengths and limitations of specific research designs including randomised controlled trials, cohort studies, case control studies and much more.

The following sections cover reporting guidelines, writing a good research paper, sample size calculations, subgroup analyses and associated topics such as research ethics and patient consent.

The second edition has been fully revised and expanded and includes new advanced content. Clinical images and figures further enhance the comprehensive text.

Key points

New edition providing guidance on latest clinical research techniques and publishing in medical literature
Fully revised and expanded content with new advanced topics
Internationally recognised author team
Previous edition (9788184488906) published in 2010

Contents:

Section 1: The Basics

The Origins of Evidence-based Medicine
Why do We Need Evidence-based Medicine
Tips to becoming an Evidence-based Clinician
Quality of Evidence-has it Improved?

Section 2: Choosing the Right Study Design

Levels of Evidence-A Quick Guide
Level 1 Evidence-Randomized Controlled Trials
Level 2 Evidence-Prospective Cohort Studies
Level 3 Evidence-Case-control Studies
Level 4 Evidence-Clinical Case Series
Level 5 Evidence-Surveys

Section 3: Special Designs and Topics

The Basics of Systematic Reviews and Meta-analysis
The Basics of Economic Evaluation
The Basics of a Diagnostic Test Study
The Basics of Reliability
Quick Guide to Assess Risk of Bias in Randomized Controlled Trials
GRADE-Understanding Grades of Healthcare Recommendations

Section 4: The Research Protocol

First Things First-The Research Proposal
Choosing the Outcome-A Primer
Common Quality of Life and Health Utility Outcome Tools
An Introduction to Sample Size
Estimating an Appropriate Sample Size-Advanced Concepts, Formulae and Examples
Planning your Analysis-Keep it Simple
What are Subgroup Analyses and How Should You Interpret Them?

Section 5: Doing Research

Study Roles-Who does What?
Research Ethics Approval-A must Before any Clinical Trial
Why do we Need Patient Consent? Designing a Good Consent Form
Collecting Data-It all Begins with a Good Data Form

Section 6: Getting the Word Out- Presentation and Publication

Creating an Impactful Slide Presentation
Writing a Good Clinical Research Paper
Making Sense of Reporting Guidelines
Submitting a Paper for Publication-A Guide to Success
Knowledge Translation 101-Maximizing Impact

Glossary

Index