Main description:

This unique synthesis of chapters from top experts in their fields, targets the very important and upcoming area of cancer biomarkers and the need for better and more rigorous design and clinical trial. The book covers several aspects of cancer molecular markers from innovation, screening, controversies and future directions. The primary target audience for the book includes PhD and MD students, researchers, biologists, medical doctors and professionals who are interested in mechanistic studies on cancer diagnosis and translational benefits from personalized cancer treatment using the new era of biomarkers.

Contents:

Improving Research on Biomarkers for Early Detection and Screening of Cancers. Biomarkers of Oxidative Stress in Carcinogenesis. ss-Catenin: a Novel Biomarker and Therapeutic Target in Liver Cancer. Urine Biomarkers for Prostate Cancer Detection. Ectodomain Shedding as a Mechanism to Generate Cancer Biomarkers (Ectomarkers). The BRCT Signaling 'landscape': Emerging Concepts and Implications in Tumorigenesis and Cancer Diagnostics. Cellular Senescence and Cancer Development: Antagonistic and Synergistic Relations. Micro-RNAs: From Regulators of Gene Expression to Cancer Biomarkers. Targeting PARP-1 in Breast Cancer: The Paradigm of a DNA Repair-based Therapeutic Strategy. Statins in Prostate Cancer: Prevention and Treatment. Mechanistic Aspects of Oxidative Stress Involvement in Human Environmental and Occupational Carcinogenesis.