This book reviews the natural course of arteriovenous malformation (AVM) disease and the active treatment modalities. These are compared with surgical and neuropsychological results achieved at the Military University Hospital, Prague, Czech Republic. Based on these comparisons, treatment recommendation for AVM is articulated. Furthermore, the long-term efficacy of different treatment is discussed. This book is written by an international group of European authors, and is aimed at neurovascular surgeons and neurosurgical residents.
Introduction.- Motivation to this study.- AVM definition and angioarchitecture.- Feeding arteries.- Associated aneurysms.- Nidus component.- Draining veins.- Genetics of arteriovenous malformations.- Epidemiology of AVM.- Physiology of arteriovenous malformations.- Arterial side.- Steal phenomenon.- Normal perfusion pressure breakthrough.- Venous side.- Occlusive hyperemia.- Compartmental model of AVM nidus.- AVM presentation.- Hemorrhagic presentation.- Morbidity and mortality of AVM related intracranial haemorrhage.- Epilepsy presentation.- Focal neurologic deficit (FND).- Natural course.- AVM grading.- Surgical AVM grading.- Radiosurgical AVM grading.- Imaging.- Catheter angiography.- Magnetic resonance imaging.- Computed tomography.- Treatment for brain AVMs.- Literature series.- Surgery.- Endovascular embolization.- Stereotactic radiosurgery.- Combined treatment.- ARUBA study comments.